The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
Aug. 12, 2015
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Lilli Anselm, Binzen, DE;
Bjoern Bartels, Schopfheim, DE;
Cosimo Dolente, Allschwil, CH;
Wolfgang Guba, Muellheim, DE;
Haap Wolfgang, Loerrach, DE;
Jens-Uwe Peters, Grenzach-Wyhlen, DE;
Thomas Woltering, Freiburg, DE;
Ulrike Obst Sander, Reinach, CH;
Mark Rogers-Evans, Bottmingen, CH;
Assignee:
HOFFMANN-LA ROCHE INC., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01);
Abstract
The present invention provides a compound of formula (I) having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.