The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 13, 2018

Filed:

Jun. 10, 2013
Applicant:

Lanzatech New Zealand Limited, Auckland, NZ;

Inventors:

Alexander Paul Mueller, Auckland, NZ;

Michael Koepke, Auckland, NZ;

Shilpa Nagaraju, Auckland, NZ;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 9/04 (2006.01); C12N 9/88 (2006.01); C12N 15/74 (2006.01); C12P 7/16 (2006.01);
U.S. Cl.
CPC ...
C12N 15/74 (2013.01); C12N 1/20 (2013.01); C12N 9/0006 (2013.01); C12N 9/88 (2013.01); C12P 7/16 (2013.01); C12Y 101/01004 (2013.01); C12Y 402/0103 (2013.01); C12Y 402/01028 (2013.01); Y02E 50/10 (2013.01);
Abstract

Carboxydotrophic acetogenic microorganisms do not produce MEK and/or 2-butanol. They lack the biosynthesis pathways to make these products. In addition, they produce the intermediate (R,R)-2,3-butanediol whereas the production of MEK and 2-butanol requires production of the intermediate (R,S)-2,3-butanediol. Nonetheless, the production of MEK and/or 2-butanol can be accomplished using recombinant microorganisms adapted to express or overexpress key enzymes in the MEK and/or 2-butanol biosynthesis pathways. Such microorganisms, such as the carboxydotrophic acetogen, can ferment substrates comprising CO. The overall scheme involves the production of 2-butanol from (R,S)-2,3-butanediol and the conversion of (R)-acetoin to (S)-2,3-butanediol. These steps are involved in the production of both MEK and 2-butanol. Such fermentation methods offer a means of using carbon monoxide from industrial processes which would otherwise be released into the atmosphere and pollute the environment.


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