The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2018
Filed:
Mar. 15, 2013
Alderbio Holdings Llc, Las Vegas, NV (US);
Benjamin H. Dutzar, Seattle, WA (US);
Brian R. Kovacevich, Snohomish, WA (US);
Patricia Dianne McNeill, Federal Way, WA (US);
Danielle M. Mitchell, Seattle, WA (US);
Ethan W. Ojala, Snohomish, WA (US);
Pei Fan, Bothell, WA (US);
Jens Billgren, Seattle, WA (US);
Erica A. Stewart, Shoreline, WA (US);
Corinne C. Akatsuka, Hilo, HI (US);
Betty Yu-Ching Chang, Cupertino, CA (US);
John A. Latham, Seattle, WA (US);
Leon F. Garcia-Martinez, Woodinville, WA (US);
ALDERBIO HOLDINGS LLC, Las Vegas, NV (US);
Abstract
The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the V, Vand CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.