logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9874562 B1

PDFFull Text
Date of Patent:
Jan. 23, 2018

Filed:

Jul. 14, 2016

Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses

Applicant:

Academia Sinica, Taipei, TW;

Inventors:

Chi-Huey Wong, La Jolla, CA (US);

Jim-Min Fang, Taipei, TW;

Yih-Shyun Edmund Cheng, Taipei, TW;

Jiun-Jie Shie, Taipei, TW;

Assignee:

ACADEMIA SINICA, Taipei, TW;

Attorneys:

Duane Morris LLP

Vicki G. Norton

Ryan C. Smith

Primary Examiner:

Joseph R Kosack

Int. Cl.
CPC ...
G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56983 (2013.01); G01N 2333/11 (2013.01);
Abstract

Methods and compositions for detection of drug resistant pathogens and treatment against infections thereof are provided. Methods for detection of oseltamivir-resistant influenza viruses by competitive binding assays utilizing non-oseltamivir influenza virus neuraminidase inhibitors and oseltamivir carboxylate are provided. Influenza virus neuraminidase inhibitors coupled to sensors and useful for employment in the methods of the invention are disclosed. Novel phosphonate compounds active as neuraminidase inhibitors against wild-type and oseltamivir-resistant influenza strains of H1N1, H5N1 and H3N2 viruses are disclosed. An enantioselective synthetic route to preparation of these phosphonate compounds via sialic acid is provided.

Find Patent Forward Citations

Wong, Chi-Huey. (2018). Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses (U.S. Patent No. 9874562). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9874562

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…