The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2018

Filed:

Jan. 29, 2014
Applicant:

Danisco Us Inc., Palo Alto, CA (US);

Inventors:

Mark A. Emalfarb, Jupiter, FL (US);

Peter J. Punt, Houten, NL;

Cornelia Van Zeijl, Vleuten-de-Meern, NL;

Cornelius Van den Hondel, Gouda, NL;

Jan Cornelis Verdoes, Bennekom, NL;

Richard P. Burlingame, Jupiter, FL (US);

Assignee:

DANISCO US INC., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/80 (2006.01); C40B 40/06 (2006.01); C12P 21/00 (2006.01); G01N 33/561 (2006.01);
U.S. Cl.
CPC ...
C12N 15/80 (2013.01); C12P 21/00 (2013.01); C40B 40/06 (2013.01); G01N 33/561 (2013.01);
Abstract

The invention is generally directed to modified filamentous fungal host cells comprising one or more nucleic acids encoding one or more polypeptides under the control of one or more promoters that are functional in said cells. Methods of using the modified cells to express one or more polypeptides are also disclosed, including methods of screening cells transformed with one or more expression vectors comprising nucleic acids derived from synthetic or genomic nucleic acids including, cDNAs. Methods of purifying one or more polypeptides or complexes comprising one or more polypeptides expressed in the modified cells, intended for use as substrates in structure/function studies, as therapeutic agents, as diagnostic reagents, or as human or animal vaccines, are also disclosed.


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