The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2017

Filed:

Mar. 17, 2014
Applicants:

Kazusa Dna Research Institute, Kisarazu-shi, Chiba, JP;

Animal Allergy Clinical Laboratories Inc., Sagamihara-shi, Kanagawa, JP;

Nippon Zenyaku Kogyo Co., Ltd., Koriyama-shi, Fukushima, JP;

Inventors:

Osamu Ohara, Kisarazu, JP;

Takahiro Nagase, Kisarazu, JP;

Yoshihiro Yamaguchi, Kisarazu, JP;

Reiko Ohara, Kisarazu, JP;

Kenichi Masuda, Sagamihara, JP;

Toshihiro Tsukui, Koriyama, JP;

Assignees:

KAZUSA DNA RESEARCH INSTITUTE, Kisarazu-Shi, Chiba, JP;

ANIMAL ALLERGY CLINICAL LABORATORIES INC., Sagamihara-Shi, Kanagawa, JP;

NIPPON ZENYAKU KOGYO CO., LTD., Koriyama-Shi, Fukushima, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/42 (2006.01); C12N 15/85 (2006.01); G01N 33/577 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/4291 (2013.01); C12N 15/8509 (2013.01); G01N 33/577 (2013.01); G01N 33/6854 (2013.01); A01K 2217/052 (2013.01); A01K 2227/706 (2013.01); A01K 2267/01 (2013.01); C07K 2317/14 (2013.01); C07K 2317/52 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/624 (2013.01); C07K 2317/626 (2013.01); C07K 2319/21 (2013.01); C12N 2015/8518 (2013.01);
Abstract

Problem to be Solved: The present invention is intended to provide a polynucleotide encoding the light-chain variable region and the heavy-chain variable region of an anti-dog IgE antibody; and an anti-dog IgE antibody containing these variable regions. Solution: The present invention is DNA encoding a heavy-chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 2 or 6 and DNA encoding a light-chain variable region consisting of the amino acid sequence represented by SEQ ID NO: 4 or 8, and an anti-dog IgE monoclonal antibody which binds to dog IgE, containing these variable regions or a functional fragment thereof which binds to dog IgE.


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