The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 19, 2017
Filed:
Jun. 17, 2015
Applicants:
Umesh K. Jinwal, Tampa, FL (US);
Diego A. Peralta, Pembroke Pines, FL (US);
Malathi Narayan, Tampa, FL (US);
Inventors:
Umesh K. Jinwal, Tampa, FL (US);
Diego A. Peralta, Pembroke Pines, FL (US);
Malathi Narayan, Tampa, FL (US);
Assignee:
University of South Florida, Tampa, FL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/055 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/055 (2013.01); A61K 45/06 (2013.01);
Abstract
A method of treating TDP-43 proteinopathies such as Alzheimer's disease, amyotrophic lateral sclerosis, and fronto-temporal lobar dementia is presented herein. It was found that administering hexachlorophene to cells expressing endogenous TDP-43 or overexpressing wild-type TDP-43 reduced accumulation of TDP-43 in the cells.