The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2017

Filed:

Dec. 18, 2015
Applicant:

Dsm Ip Assets B.v., Heerlen, NL;

Inventors:

Paul W Behrens, Ellicott City, MD (US);

John M Thompson, Baltimore, MD (US);

Kirk Apt, Ellicott City, MD (US);

Joseph W. Pfeifer, III, Westminster, MD (US);

James P Wynn, Okemos, MI (US);

James Casey Lippmeier, Columbia, MD (US);

Jaouad Fichtali, Lexington, KY (US);

Jon Hansen, West Friendship, MD (US);

Assignee:

DSM IP Assets B.V., TE Heerlen, NL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/64 (2006.01); A61K 36/02 (2006.01); C11B 1/10 (2006.01);
U.S. Cl.
CPC ...
C12P 7/6427 (2013.01); A61K 36/02 (2013.01); C11B 1/10 (2013.01); C12P 7/6409 (2013.01); C12P 7/6472 (2013.01);
Abstract

Methods for production of highly unsaturated fatty acids by marine microorganisms, including the heterotrophic marine dinoflagellate, using low levels of chloride ion are disclosed. Specifically, methods of increasing production of highly unsaturated fatty acids by marine microorganisms while growing in low chloride media by manipulating sodium ion and potassium ion levels. The invention also relates to methods of production of highly unsaturated fatty acids by marine organisms at low pH levels, and includes methods for generation of low pH tolerant strains.


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