The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2017
Filed:
May. 24, 2011
Michael Patrik Katz, Malmo, SE;
Thomas Durhuus, Copenhagen, DK;
Hans Peter Smits, Holte, DK;
Jochen Förster, Copenhagen V, DK;
Michael Patrik Katz, Malmo, SE;
Thomas Durhuus, Copenhagen, DK;
Hans Peter Smits, Holte, DK;
Jochen Förster, Copenhagen V, DK;
EVOLVA SA, Reinach, CH;
Abstract
A recombinant micro-organism such aswhich produces and excretes into culture medium a stilbenoid metabolite product when grown under stilbenoid production conditions, which expresses in above native levels a ABC transporter which transports said stilbenoid out of said micro-organism cells to the culture medium. The genome of theproduces an auxotrophic phenotype which is compensated by a plasmid which also expresses one or more of said enzymes constituting said metabolic pathway producing said stilbenoid, an expression product of the plasmid is genetically modified to include a ubiquitination tag sequence. Expression of an enzyme participating in catabolism of phenylalanine by the Ehrlich pathway is optionally reduced compared to its native expression level.