The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2017
Filed:
Aug. 19, 2015
Jennifer Brogdon, Cambridge, MA (US);
Saar Gill, Philadelphia, PA (US);
David Glass, Cambridge, MA (US);
Saad Kenderian, Philadelphia, PA (US);
Andreas Loew, Cambridge, MA (US);
Joan Mannick, Cambridge, MA (US);
Michael C. Milone, Cherry Hill, NJ (US);
Leon Murphy, Cambridge, MA (US);
David L. Porter, Springfield, PA (US);
Marco Ruella, Philadelphia, PA (US);
Yongqiang Wang, Shanghai, CN;
Qilong Wu, Shanghai, CN;
Jiquan Zhang, Shanghai, CN;
Jennifer Brogdon, Cambridge, MA (US);
Saar Gill, Philadelphia, PA (US);
David Glass, Cambridge, MA (US);
Saad Kenderian, Philadelphia, PA (US);
Andreas Loew, Cambridge, MA (US);
Joan Mannick, Cambridge, MA (US);
Michael C. Milone, Cherry Hill, NJ (US);
Leon Murphy, Cambridge, MA (US);
David L. Porter, Springfield, PA (US);
Marco Ruella, Philadelphia, PA (US);
Yongqiang Wang, Shanghai, CN;
Qilong Wu, Shanghai, CN;
Jiquan Zhang, Shanghai, CN;
Novartis AG, Basel, CH;
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Abstract
The invention provides compositions and methods for treating diseases associated with expression of CD123. The invention also relates to chimeric antigen receptor (CAR) specific to CD123, vectors encoding the same, and recombinant cells comprising the CD123 CAR. The invention also includes methods of administering a genetically modified cell expressing a CAR that comprises a CD123 binding domain.