The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2017
Filed:
Jul. 13, 2012
Ko Rii, Chofu, JP;
Kazuo Sakurai, Himeji, JP;
Masakazu Kobayashi, Kawanishi, JP;
Hironori Ando, Nishitokyo, JP;
Sadaharu Higuchi, Nishitokyo, JP;
Shiro Takahara, Ikeda, JP;
Ko Rii, Chofu, JP;
Kazuo Sakurai, Himeji, JP;
Masakazu Kobayashi, Kawanishi, JP;
Hironori Ando, Nishitokyo, JP;
Sadaharu Higuchi, Nishitokyo, JP;
Shiro Takahara, Ikeda, JP;
Napajen Pharma, Inc., Burlingame, CA (US);
Abstract
An object of the present invention is to provide a drug and a method for effectively inducing donor-specific immune tolerance in a recipient in transplantation therapy. A complex of an siRNA for a costimulatory factor and schizophyllan is delivered to a Dectin-1 expressing cell which specifically recognizes schizophyllan to regulate the function of the Dectin-1 expressing cell, and therefore can induce immunosuppression effect as well as induce immune tolerance effectively.