The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2017

Filed:

Jan. 12, 2016
Applicants:

President and Fellows of Harvard College, Cambridge, MA (US);

University of Washington, Seattle, WA (US);

Inventors:

George M. Church, Brookline, MA (US);

Justin Feng, Cambridge, MA (US);

Daniel J. Mandell, Brookline, MA (US);

David Baker, Seattle, WA (US);

Stanley Fields, Seattle, WA (US);

Benjamin Ward Jester, Seattle, WA (US);

Christine Elaine Tinberg, Seattle, WA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
G01N 33/743 (2013.01); G01N 2500/10 (2013.01);
Abstract

Disclosed is a biosensor engineered to conditionally respond to the presence of specific small molecules, the biosensors including conditionally stable ligand-binding domains (LBDs) which respond to the presence of specific small molecules, wherein readout of binding is provided by reporter genes or transcription factors (TFs) fused to the LBDs.


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