The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2017
Filed:
May. 11, 2015
Applicant:
The Rockefeller University, New York, NY (US);
Inventors:
Tom W. Muir, Princeton, NJ (US);
Jung-Min Kee, Plainsboro, NJ (US);
Assignee:
THE ROCKEFELLER UNIVERSITY, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); A61K 31/675 (2006.01); C07F 9/6518 (2006.01); A61K 47/48 (2006.01); C07D 249/04 (2006.01); C07F 9/40 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); A61K 31/675 (2013.01); A61K 47/4833 (2013.01); A61K 47/48061 (2013.01); C07F 9/65182 (2013.01); C07F 9/65186 (2013.01); C07D 249/04 (2013.01); C07F 9/4015 (2013.01); C07K 2317/34 (2013.01);
Abstract
The present invention relates to the phosphohistidine analogs of the present invention which of the formula and the hapten containing the residue of same. It also relates to the hapten conjugated to a carrier molecule and the isolated antibodies raised against the immunogens, said antibodies recognizing polypeptide containing a phosphorylated histidine or the phosphotriazole residue but it does not recognize an amino acid or polypeptide that is not phosphorylated or a polypeptide which is phosphorylated on amino acids other than histidine but not on histidine.