The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2017

Filed:

Oct. 29, 2015
Applicant:

Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;

Inventors:

Yasuyuki Takeda, Shinagawa-ku, JP;

Kenji Yoshikawa, Shinagawa-ku, JP;

Yoshiko Kagoshima, Shinagawa-ku, JP;

Yuko Yamamoto, Shinagawa-ku, JP;

Ryoichi Tanaka, Shinagawa-ku, JP;

Yuichi Tominaga, Shinagawa-ku, JP;

Masaki Kiga, Shinagawa-ku, JP;

Yoshito Hamada, Shinagawa-ku, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

The present invention is intended to provide a compound or a pharmacologically acceptable salt thereof which is useful in the treatment of a tumor through its ROS1 kinase enzyme activity inhibitory effect and NTRK kinase enzyme inhibitory effect. The present invention provides a compound having an imidazo[1,2-b]pyridazine structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, and a pharmaceutical composition comprising the compound. In the formula, R, G, T, Y, Y, Y, and Yare as defined herein.


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