The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2017
Filed:
Feb. 04, 2010
Applicants:
Tod M. Woolf, Sudbury, MA (US);
Joanne Kamens, Newton, MA (US);
William Salomon, Worcester, MA (US);
Anastasia Khvorova, Westborough, MA (US);
Inventors:
Tod M. Woolf, Sudbury, MA (US);
Joanne Kamens, Newton, MA (US);
William Salomon, Worcester, MA (US);
Anastasia Khvorova, Westborough, MA (US);
Assignee:
RXi Pharmaceuticals Corporation, Marlborough, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/713 (2006.01); A61K 48/00 (2006.01); C12N 15/113 (2010.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/111 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/3515 (2013.01); C12N 2310/3519 (2013.01); C12N 2310/533 (2013.01); C12N 2320/51 (2013.01);
Abstract
The present invention relates to RNAi constructs and their use in gene silencing. RNAi constructs associated with the invention contain a double stranded region connected to a single stranded region of phosphorothioate modified nucleotides.