The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2017

Filed:

Jan. 09, 2015
Applicant:

Jiangsu Academy of Agricultural Sciences, Jiangsu, CN;

Inventors:

Xianjin Liu, Jiangsu, CN;

Chongxin Xu, Jiangsu, CN;

Xiao Zhang, Jiangsu, CN;

Yuan Liu, Jiangsu, CN;

Yajing Xie, Jiangsu, CN;

Cunzheng Zhang, Jiangsu, CN;

Xiangyang Yu, Jiangsu, CN;

Donglan Wang, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/42 (2006.01); A01N 63/02 (2006.01); C07K 16/12 (2006.01); A01N 57/16 (2006.01);
U.S. Cl.
CPC ...
C07K 16/4233 (2013.01); A01N 57/16 (2013.01); A01N 63/02 (2013.01); C07K 16/1278 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01);
Abstract

An anthropogenic insect-resistant gene having a nucleotide sequence represented by SEQ ID NO.1, and a Cry1C toxin idiotype single-chain antibody encoded by said anthropogenic insect-resistant gene and having an amino acid sequence represented by SEQ ID NO.2; the antibody is a β-type and has insecticidal activity, and after expression by the prokaryotic system, the primary culture thereof has binding activity tomidgut peritrophic membrane specific receptor BBMV; the β-type Cry1C toxin idiotype single-chain antibody of the present invention is obtained without animal immunization, has a short preparation period and small amino acid sequence, and is suitable for large-scale in vitro production. The present invention is an entirely new insect-resistant gene resource, and has significant implications for decreasing the various safety risks associated with the widescale use of existing Bt toxins, substituting Bt toxins in the biocontrol of agricultural pests, and reducing the use of pesticides.


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