The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2017
Filed:
Dec. 18, 2013
Steffen Schaffer, Herten, DE;
Jasmin Gielen, Bochum, DE;
Mirja Wessel, Bochum, DE;
Hans-georg Hennemann, Marl, DE;
Harald Haeger, Luedinghausen, DE;
Thomas Haas, Muenster, DE;
Wilfried Bluemke, Schoeneck, DE;
Steffen Schaffer, Herten, DE;
Jasmin Gielen, Bochum, DE;
Mirja Wessel, Bochum, DE;
Hans-Georg Hennemann, Marl, DE;
Harald Haeger, Luedinghausen, DE;
Thomas Haas, Muenster, DE;
Wilfried Bluemke, Schoeneck, DE;
Evonik Degussa, Essen, DE;
Abstract
The invention provides a whole cell catalyst which expresses a recombinant α-dioxygenase or the combination of a recombinant fatty acid reductase and a phosphopantetheinyl transferase phosphopantetheinylating the fatty acid reductase, and which in addition to the α-dioxygenase and/or the combination of fatty acid reductase and phosphopantetheinyl transferase expresses a transaminase, characterized in that the phosphopantetheinyl transferase and/or transaminase is preferably recombinant; and a method for the conversion of a fatty acid, ω-hydroxy fatty acid, ω-oxo fatty acid or a monoester thereof to an amine, comprising oxidation of the fatty acid, ω-hydroxy fatty acid, ω-oxo fatty acid or the monoester thereof to an oxidation product by contacting with an alkane hydroxylase and/or alcohol dehydrogenase, contacting the oxidation product with a phosphopantetheinylated fatty acid reductase or a α-dioxygenase to give an aldehyde, and contacting the aldehyde with a transaminase.