The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2017
Filed:
Feb. 09, 2015
Biogen MA Inc., Cambridge, MA (US);
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);
C. Frank Bennett, Carlsbad, CA (US);
Gene Hung, San Diego, CA (US);
Frank Rigo, Carlsbad, CA (US);
Adrian R. Krainer, Huntington Square, NY (US);
Yimin Hua, Jericho, NY (US);
Marco A. Passini, Shrewsbury, MA (US);
Lamya Shihabuddin, Brighton, MA (US);
Seng H. Cheng, Natick, MA (US);
Katherine W. Klinger, Sudbury, MA (US);
Biogen MA Inc., Cambridge, MA (US);
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (US);
Abstract
Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a subject. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders, including spinal muscular atrophy.