The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2017

Filed:

Aug. 16, 2013
Applicants:

American Air Liquide, Inc., Fremont, CA (US);

The United States of America As Represented BY the Secretary, Dept. of Health and Human Svcs., National Institutes of Health, Washington, DC (US);

Inventors:

Vasuhi Rasanayagam, Newark, DE (US);

Sagar D. Joshi, Newark, DE (US);

Meenakshi Sundaram, Newark, DE (US);

Stephen M. Hewitt, Rockville, MD (US);

Joon-Yong Chung, Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/04 (2006.01); B01J 19/00 (2006.01); C12Q 1/68 (2006.01); A01N 1/00 (2006.01);
U.S. Cl.
CPC ...
C12N 1/04 (2013.01); A01N 1/00 (2013.01); C12Q 1/6806 (2013.01);
Abstract

The invention may be broadly defined as the addition of Argon to FFPE procedures as an RNA stabilizing agent. Argon is an inert gas from the Noble gas group with low saturation concentrations in water. It is therefore highly surprising that Argon would have any effect on RNA stability in the presence of Formalin, or any other chemical. This property of Argon appears to be specific in that other inert gases fail to show any RNA stabilizing effect.


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