The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2017
Filed:
Feb. 15, 2012
Applicants:
Ko Rii, Chofu, JP;
Kazuo Sakurai, Himeji, JP;
Masakazu Kobayashi, Kawanishi, JP;
Hironori Ando, Nishitokyo, JP;
Sadaharu Higuchi, Nishitokyo, JP;
Shiro Takahara, Ikeda, JP;
Inventors:
Ko Rii, Chofu, JP;
Kazuo Sakurai, Himeji, JP;
Masakazu Kobayashi, Kawanishi, JP;
Hironori Ando, Nishitokyo, JP;
Sadaharu Higuchi, Nishitokyo, JP;
Shiro Takahara, Ikeda, JP;
Assignee:
NAPAJEN PHARMA, INC., Burlingame, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 39/00 (2006.01); A61K 31/7105 (2006.01); A61K 31/716 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0013 (2013.01); A61K 31/7105 (2013.01); A61K 31/716 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/1138 (2013.01); A61K 2039/57 (2013.01); C12N 2310/315 (2013.01); C12N 2320/32 (2013.01); C12N 2320/50 (2013.01);
Abstract
A highly stable nucleic acid-polysaccharide complex of an siRNA and schizophyllan is formed by adding polydeoxyadenine in which at least part of the phosphodiester link portion is phosphorothioated to an siRNA and allowing the siRNA and schizophyllan to form a complex.