The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2017
Filed:
Feb. 04, 2014
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Matthew P. Christopher, Brookline, MA (US);
Francesc Xavier Fradera Llinas, Brookline, MA (US);
Michelle Machacek, Brookline, MA (US);
Michelle Martinez, Watertown, MA (US);
Michael Hale Reutershan, Brighton, MA (US);
Manami Shizuka, Lexington, MA (US);
Binyuan Sun, Needham Heights, MA (US);
Christopher Francis Thompson, Arlington, MA (US);
B. Wesley Trotter, Medfield, MA (US);
Matthew E. Voss, Singapore, SG;
Liping Yang, Arlington, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention provides 2,6,7 substituted purines as described herein or a pharmaceutically acceptable salt thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.