The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2017
Filed:
Jan. 08, 2016
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Georg Jaeschke, Basel, CH;
Lothar Lindemann, Basel, CH;
Rainer E. Martin, Basel, CH;
Antonio Ricci, Biel-Benken, CH;
Daniel Rueher, Raedersdorf, FR;
Heinz Stadler, Aadorf, CH;
Eric Vieira, Frenkendorf, CH;
Assignee:
HOFFMANN-LA ROCHE INC., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); C07D 401/04 (2013.01);
Abstract
The present invention relates to ethynyl derivatives as metabotropic glutamate receptor antagonists (negative allosteric modulators) for use in the treatment of, e.g., anxiety and pain, depression, Fragile-X syndrome, autism spectrum disorders, Parkinson's disease, and gastroesophageal reflux disease (GERD).