The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2017
Filed:
Nov. 03, 2014
Hemarus Therapeutics Limited, Hyderabad, IN;
Neelima Vadde, Hyderabad, IN;
Mitali Samaddar, Hyderabad, IN;
Ashok Nuvula, Hyderabad, IN;
Zinia Chakraborty, Hyderabad, IN;
Swapna Sagar Duggineni, Hyderabad, IN;
Uma Devi Komath, Hyderabad, IN;
HEMARUS THERAPEUTICS LIMITED, Hyderabad, IN;
Abstract
The invention is an integrated process for the isolation and purification of plasma derived clotting Factor VIII, clotting Factor IX, albumin and immunoglobulin without the use of ethanol precipitation. The integrated process comprises of sequential chromatography steps of gel filtration, anion exchange and cation exchange chromatographies, followed by viral inactivation and removal steps. The present invention has the advantage of being a mild process that does not denature or aggregate the proteins and provides high yields of several therapeutic grade plasma proteins from a given volume of plasma.