The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2017

Filed:

Dec. 03, 2013
Applicant:

The University of Hong Kong, Hong Kong, CN;

Inventors:

Chaminda Jayampath Seneviratne, Hong Kong, CN;

Yi Tsun Richard Kao, Hong Kong, CN;

Lakshman Perera Samaranayake, Hong Kong, CN;

Kwok Yung Yuen, Hong Kong, CN;

Dan Yang, Hong Kong, CN;

Yu Wang, Hong Kong, CN;

Sze Wah Sarah Wong, Hong Kong, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 309/34 (2006.01); A61K 31/351 (2006.01); A01N 43/40 (2006.01); A01N 59/00 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/351 (2013.01); A01N 43/40 (2013.01); A01N 59/00 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01);
Abstract

Disclosed herein is a novel antifungal compound, derivatives that are used to treat fungal infections. In a specific embodiment, the compound is a small molecule. In a specific embodiment, the compound described herein inhibits yeast to hypha transition under robust hyphal inducing conditions at lower concentration of the molecule. Also disclosed is a composition comprising the antifungal compound. In a specific embodiment, the composition is a pharmaceutical composition. Also disclosed is a method of treating and/or preventing fungal infection using the disclosed compound. The disclosed compound exhibits antifungal activity against wide range of fungal species at slightly higher concentrations. Antifungal compound disclosed herein is used as anti-biofilm agent against fungal infections.


Find Patent Forward Citations

Loading…