The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 18, 2017

Filed:

Jun. 27, 2014
Applicants:

University of Washington, Seattle, WA (US);

The Uab Research Foundation, Birmingham, AL (US);

Inventors:

Jens H. Gundlach, Seattle, WA (US);

Michael Niederweis, Homewood, AL (US);

Thomas Z. Butler, Seattle, WA (US);

Mikhail Pavlenok, Birmingham, AL (US);

Mark A. Troll, Seattle, WA (US);

Suja Sukumaran, Dublin, CA (US);

Assignees:

University of Washington, Seattle, WA (US);

The UAB Research Foundation, Birmingham, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/04 (2006.01); A61K 39/02 (2006.01); C12Q 1/70 (2006.01); C07K 14/35 (2006.01); C12N 13/00 (2006.01); G01N 33/68 (2006.01); C12Q 1/68 (2006.01); G01N 27/447 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
C07K 14/35 (2013.01); C12N 13/00 (2013.01); C12Q 1/6869 (2013.01); G01N 27/44704 (2013.01); G01N 33/6872 (2013.01); A61K 39/04 (2013.01); G01N 33/48721 (2013.01);
Abstract

Provided herein areporin nanopores, systems that comprise these nanopores, and methods of using and making these nanopores. Such nanopores may be wild-type MspA porins, mutant MspA porins, wild-type MspA paralog porins, wild-type MspA homolog porins, mutant MspA paralog porins, mutant MspA homolog porins, or single-chain Msp porins. Also provided are bacterial strains capable of inducible Msp porin expression.


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