The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 28, 2017
Filed:
May. 05, 2011
William Ryan Sillers, Lebanon, NH (US);
Hans Van Dijken, Schiedam HG, NL;
Steve Licht, Utica, NY (US);
Arthur J. Shaw, Iv, Grantham, NH (US);
Alan Benjamin Gilbert, Lebanon, NH (US);
Aaron Argyros, White River Junction, VT (US);
Allan C. Froehlich, Lebanon, NH (US);
John E. Mcbride, Lyme, NH (US);
Haowen Xu, Lebanon, NH (US);
David A. Hogsett, Lebanon, NH (US);
Vineet B. Rajgarhia, Lebanon, NH (US);
William Ryan Sillers, Lebanon, NH (US);
Hans Van Dijken, Schiedam HG, NL;
Steve Licht, Utica, NY (US);
Arthur J. Shaw, IV, Grantham, NH (US);
Alan Benjamin Gilbert, Lebanon, NH (US);
Aaron Argyros, White River Junction, VT (US);
Allan C. Froehlich, Lebanon, NH (US);
John E. McBride, Lyme, NH (US);
Haowen Xu, Lebanon, NH (US);
David A. Hogsett, Lebanon, NH (US);
Vineet B. Rajgarhia, Lebanon, NH (US);
Lallemand Hungary Liquidity Management LLC, Budapest, HU;
Abstract
One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce lactate or acetate as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non-native gene encodes a first non-native enzyme involved in the metabolic production of lactate or acetate. Another aspect of the invention relates to a process for converting lignocellulosic biomass to lactate or acetate, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.