The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 2017

Filed:

Mar. 15, 2013
Applicant:

Pronutria, Inc., Cambridge, MA (US);

Inventors:

Geoffrey von Maltzahn, Boston, MA (US);

Michael J. Hamill, Wellesley, MA (US);

Rajeev Chillakuru, Cambridge, MA (US);

John F. Kramarczyk, Somerville, MA (US);

David Arthur Berry, Brookline, MA (US);

Brett Adam Boghigian, Boston, MA (US);

Nathaniel W. Silver, Cambridge, MA (US);

Assignee:

Axcella Health Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); A61K 38/00 (2006.01); C07K 14/47 (2006.01); A23J 3/04 (2006.01); C07K 14/415 (2006.01); A23L 33/175 (2016.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); A23J 3/04 (2013.01); A23L 33/175 (2016.08); C07K 14/415 (2013.01); A61K 38/00 (2013.01);
Abstract

Nutritive proteins are provided. In some embodiments the nutritive proteins comprise at least one of a level of a) a ratio of branch chain amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of branch chain amino acid residues to total amino acid residues present in whey protein; b) a ratio of leucine residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of leucine residues to total amino acid residues present in whey protein; and c) a ratio of essential amino acid residues to total amino acid residues present in the nutritive protein equal to or greater than the ratio of essential amino acid residues to total amino acid residues present in whey protein. Also provided are nucleic acids encoding the proteins, recombinant microorganisms that make the proteins, methods of making the proteins using recombinant microorganisms, compositions that comprise the proteins, and methods of using the proteins, among other things.


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