The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2017

Filed:

Nov. 30, 2015
Applicants:

John Tomesch, Succasunna, NJ (US);

Lawrence P. Wennogle, Hillsborough, NJ (US);

Inventors:

John Tomesch, Succasunna, NJ (US);

Lawrence P. Wennogle, Hillsborough, NJ (US);

Assignee:

INTRA-CELLULAR THERAPIES, INC., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 471/22 (2006.01); C07D 471/16 (2006.01); C07C 309/30 (2006.01);
U.S. Cl.
CPC ...
C07D 471/16 (2013.01); C07C 309/30 (2013.01);
Abstract

The present invention relates to toluenesulfonic acid addition salt crystals of 4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3',4′: 4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)-1-(4-fluorophenyl)-1-butanone, and methods of using such crystals as 5-hydroxytryptamine 2 receptor agonists and antagonists in treating disorders of the central nervous system.


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