The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2017

Filed:

Dec. 08, 2014
Applicant:

B.r.a.i.n. Biotechnology Research and Information Network Ag, Zwingenberg, DE;

Inventors:

Michael Krohn, Lorsch, DE;

Holger Zinke, Heppenheim, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/35 (2006.01); A61K 31/352 (2006.01); A61K 8/41 (2006.01); A61K 8/49 (2006.01); A61K 31/00 (2006.01); A61K 31/136 (2006.01); A61K 31/137 (2006.01); A61K 31/351 (2006.01); A61K 31/4439 (2006.01); A61K 31/496 (2006.01); A61K 31/513 (2006.01); A61Q 5/00 (2006.01); A61Q 11/00 (2006.01); A61Q 17/02 (2006.01); A61Q 19/00 (2006.01); A61K 31/353 (2006.01); C07D 311/36 (2006.01);
U.S. Cl.
CPC ...
A61K 31/352 (2013.01); A23L 27/204 (2016.08); A23L 27/2052 (2016.08); A23L 27/2054 (2016.08); A23L 27/2056 (2016.08); A23L 27/88 (2016.08); A61K 8/41 (2013.01); A61K 8/411 (2013.01); A61K 8/49 (2013.01); A61K 8/498 (2013.01); A61K 8/4933 (2013.01); A61K 31/00 (2013.01); A61K 31/136 (2013.01); A61K 31/137 (2013.01); A61K 31/351 (2013.01); A61K 31/353 (2013.01); A61K 31/4439 (2013.01); A61K 31/496 (2013.01); A61K 31/513 (2013.01); A61Q 5/00 (2013.01); A61Q 11/00 (2013.01); A61Q 17/02 (2013.01); A61Q 19/00 (2013.01); C07D 311/36 (2013.01); A23V 2002/00 (2013.01); A61K 31/35 (2013.01); A61K 2800/244 (2013.01); A61K 2800/782 (2013.01); Y10T 428/249921 (2015.04);
Abstract

The present invention relates to the use of compounds which are capable of producing a cooling sensation when they are brought into contact with the human body. In particular, the present invention relates to the use of compounds modulating TRPM8, and optionally to the use of compounds selectively exhibiting agonist activity at the TRPM8 channel. Such compounds have applications in many fields, particularly in oral and personal hygiene products and foodstuffs, but also in pharmaceutical composition products, cosmetics, textile products and packaging products. The present invention further relates to products containing such compounds and to the medical use of such compounds.


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