The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2017
Filed:
Nov. 05, 2013
Suzhou Stainwei Biotech Inc., Jiangsu, CN;
Shiping Luo, Jiangsu, CN;
Hongqun Hu, Jiangsu, CN;
Zui Chen, Jiangsu, CN;
Mingwen Cai, Jiangsu, CN;
Yanan Sun, Jiangsu, CN;
Haiyun Liu, Jiangsu, CN;
Jianying Zhou, Jiangsu, CN;
Xiaoqi Song, Jiangsu, CN;
Xiaoya Ping, Jiangsu, CN;
Siyu Chen, Jiangsu, CN;
Donghong Shi, Jiangsu, CN;
Yiqing Xu, Jiangsu, CN;
Qunmin Zhou, Jiangsu, CN;
SUZHOU STAINWEI BIOTECH INC., Jiangsu, CN;
Abstract
A mouse monoclonal antibody for antagonizing and inhibiting binding of a vascular endothelial growth factor (VEGF) and its receptor (VEGF-R), and a heavy chain variable region and light chain variable region amino acid sequence thereof. Also disclosed are a humanized preparation process of the antibody and a heavy chain variable region and light chain variable region amino acid sequence of the humanized antibody. The humanized antibody or its derivative can act as an ingredient of a pharmaceutical composition or be prepared into a suitable pharmaceutical preparation, is administered alone or in combination with a chemotherapy drug or other treatment means, and is used in broad-spectrum treatment of various solid tumors such as colon cancer, breast cancer and rhabdomyosarcoma.