The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2017

Filed:

Jul. 20, 2016
Applicant:

Procos S.p.a., Cameri, IT;

Inventors:

Luigi Bogogna, Cameri, IT;

Lavinia Cicione, Novara, IT;

Alessandro Barozza, Nosate, IT;

Jacopo Roletto, Turin, IT;

Paolo Paissoni, Druento, IT;

Assignee:

PROCOS S.P.A., Cameri, IT;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/58 (2006.01);
U.S. Cl.
CPC ...
C07D 263/58 (2013.01);
Abstract

Disclosed is a process for the synthesis of chlorzoxazone (1) from 4-chloro-2-aminophenol and ethyl chloroformate in the presence of a base. The process is particularly advantageous because it uses ethyl chloroformate instead of triphosgene, a highly dangerous reagent that releases phosgene and must be handled with extremely strict procedures to guarantee the safety of operators in industrial facilities. Ethyl chloroformate allows the possibility of working with a number of solvents, including water. The yield and purity of the product obtained are very high.


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