The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 27, 2016
Filed:
Dec. 06, 2008
Taito Nishino, Tokyo, JP;
Norihisa Ishiwata, Minamisaitama-gun, JP;
Katsuaki Miyaji, Funabashi, JP;
Shunsuke Iwamoto, Funabashi, JP;
Yasuyuki Asai, Tokyo, JP;
Makiko Yui, Tokyo, JP;
Taito Nishino, Tokyo, JP;
Norihisa Ishiwata, Minamisaitama-gun, JP;
Katsuaki Miyaji, Funabashi, JP;
Shunsuke Iwamoto, Funabashi, JP;
Yasuyuki Asai, Tokyo, JP;
Makiko Yui, Tokyo, JP;
Nissan Chemical Industries, Ltd., Tokyo, JP;
ReproCELL Incorporated, Yokohama, JP;
Abstract
An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy useful for treatment of various hematopoietic disorders is provided. A method for expanding hematopoietic stem cells and/or hematopoietic progenitor cells, which comprises culturing hematopoietic stem cells and/or hematopoietic progenitor cells ex vivo in the presence of a compound represented by the formula (I) (wherein X, Y, X, Ar, R, R, R, R, R, Rand Rare defined in the description), a tautomer or pharmaceutically acceptable salt of the compound or a solvate thereof.