The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 2016
Filed:
Mar. 10, 2014
Applicant:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Inventors:
Jolanta Grembecka, Ann Arbor, MI (US);
Tomasz Cierpicki, Ann Arbor, MI (US);
Dmitry Borkin, Ann Arbor, MI (US);
Jay Hess, Ann Arbor, MI (US);
Duxin Sun, Ann Arbor, MI (US);
Xiaoqin Li, Ann Arbor, MI (US);
Assignee:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); C07D 519/00 (2006.01); C07D 495/16 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); C07D 495/16 (2013.01); C07D 519/00 (2013.01);
Abstract
The present disclosure relates generally to thienopyrimidine and thienopyridine compounds and methods of use thereof. In particular embodiments, the present disclosure provides compositions comprising thienopyrimidine and thienopyridine compounds of Formula 4b: and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins.