The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 22, 2016
Filed:
Jun. 19, 2012
Dennis Bidney, Urbandale, IA (US);
Andrew Mark Cigan, Johnston, IA (US);
Saverio Carl Falco, Wilmington, DE (US);
Huirong Gao, Johnston, IA (US);
Derek Jantz, Durham, NC (US);
Mike Lassner, Urbandale, IA (US);
Keith Lowe, Johnston, IA (US);
Leszek a Lyznik, Johnston, IA (US);
James Jefferson Smith, Durham, NC (US);
Dennis Bidney, Urbandale, IA (US);
Andrew Mark Cigan, Johnston, IA (US);
Saverio Carl Falco, Wilmington, DE (US);
Huirong Gao, Johnston, IA (US);
Derek Jantz, Durham, NC (US);
Mike Lassner, Urbandale, IA (US);
Keith Lowe, Johnston, IA (US);
Leszek A Lyznik, Johnston, IA (US);
James Jefferson Smith, Durham, NC (US);
E.I. du Pont de Nemours and Company, Wilmington, DE (US);
Pioneer Hi-Bred International, Inc., Johnston, IA (US);
Abstract
Methods of making a targeted modification in a male fertility gene in the genome of a plant are disclosed. The methods involve contacting a plant cell with an engineered double-strand-break-inducing agent capable of inducing a double-strand break in a target sequence in the male fertility gene and identifying a cell comprising an alteration in the target sequence. Also disclosed are plants, plant cells, plant parts, and seeds comprising a male fertility gene with an alteration in a male fertility gene. Nucleic acid molecules comprising male fertility genes with at least one targeted modification therein, optimized nucleic acid molecules encoding endonucleases that are engineered double-strand-break-inducing agents and expression cassettes, host cells, and plants comprising one or more of the nucleic acid molecules are further disclosed.