The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2016

Filed:

Dec. 30, 2010
Applicants:

Ming-der Wu, Hsinchu, TW;

Ming-jen Cheng, Hsinchu, TW;

Shie-jea Lin, Hsinchu, TW;

Chi-hua Chen, Hsinchu, TW;

Yen-lin Chen, Hsinchu, TW;

Hui-ping Chen, Hsinchu, TW;

Kai-ping Chen, Hsinchu, TW;

Ping-shin Yang, Hsinchu, TW;

Shiow-wen Chen, Hsinchu, TW;

Gwo-fang Yuan, Hsinchu, TW;

Inventors:

Ming-Der Wu, Hsinchu, TW;

Ming-Jen Cheng, Hsinchu, TW;

Shie-Jea Lin, Hsinchu, TW;

Chi-Hua Chen, Hsinchu, TW;

Yen-Lin Chen, Hsinchu, TW;

Hui-Ping Chen, Hsinchu, TW;

Kai-Ping Chen, Hsinchu, TW;

Ping-Shin Yang, Hsinchu, TW;

Shiow-Wen Chen, Hsinchu, TW;

Gwo-Fang Yuan, Hsinchu, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 36/062 (2006.01); A61K 31/44 (2006.01); C07D 213/80 (2006.01); C12P 17/12 (2006.01); C12R 1/645 (2006.01);
U.S. Cl.
CPC ...
A61K 36/062 (2013.01); A61K 31/44 (2013.01); A61K 45/06 (2013.01); C07D 213/80 (2013.01); C12P 17/12 (2013.01); C12R 1/645 (2013.01);
Abstract

The present invention relates to novel pyridine alkaloid compounds of formula (I): or a pharmaceutically acceptable derivative thereof as described in the specification, the process for the preparation of the same, and the composition comprising the same. The uses of a pyridine compound for increasing the activity of PPARγ, for the prevention and/or treatment of a disease or disorder related to insulin resistance, and for the prevention and/or treatment of metabolic syndrome or its complication are also provided. The invention also provides extracts of red yeast-fermented products and their uses for prevention and/or treatment of a disease or disorder related to insulin resistance, such as metabolic syndrome.


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