The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2016
Filed:
Oct. 29, 2015
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
John P. Toscano, Glen Arm, MD (US);
Daryl A. Guthrie, Baltimore, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/515 (2006.01); C07D 239/62 (2006.01); C07D 409/06 (2006.01); C07D 239/66 (2006.01);
U.S. Cl.
CPC ...
C07D 239/62 (2013.01); C07D 409/06 (2013.01); A61K 31/515 (2013.01); C07D 239/66 (2013.01);
Abstract
The present disclosure provides N-hydroxylamino-barbituric acid compounds of formulae (1)-(4), pharmaceutical compositions and kits comprising them, and methods of using such compounds or pharmaceutical compositions. The present disclosure provides methods of using such compounds or pharmaceutical compositions for treating heart failure.