The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2016
Filed:
Oct. 28, 2013
The Broad Institute, Inc., Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Edward Holson, Newton, MA (US);
Florence Fevrier Wagner, Ashland, MA (US);
Michel Weiwer, Cambridge, MA (US);
Li-Huei Tsai, Cambridge, MA (US);
Stephen Haggarty, Bridgewater, MA (US);
Yan-Ling Zhang, Lexington, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
The Broad Institute, Inc., Cambridge, MA (US);
Abstract
The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein U, J, V, X, R, R, R, Rand t are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. These compounds are useful for promoting cognitive function and enhancing learning and memory formation. In addition, these compounds are useful for treating, alleviating, and/or preventing various conditions, including for example, neurological disorders, memory and cognitive function disorders/impairments, extinction learning disorders, fungal diseases and infections, inflammatory diseases, hematological diseases, and neoplastic diseases in humans and animals.