The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2016
Filed:
Nov. 15, 2011
Darell Bigner, Mebane, NC (US);
Chien-tsun Kuan, Cary, NC (US);
Ira H. Pastan, Potomac, MD (US);
Hailan Piao, Durham, NC (US);
Darell Bigner, Mebane, NC (US);
Chien-Tsun Kuan, Cary, NC (US);
Ira H. Pastan, Potomac, MD (US);
Hailan Piao, Durham, NC (US);
The United States of America as represented by the Secretary of Health and Human Services, Washington, DC (US);
Duke University, Durham, NC (US);
Abstract
High affinity antibodies were made to gangliosides expressed on tumor cells. The antibodies can be used analytically, diagnostically, therapeutically, and theranostically. The antibodies may be used to target cytotoxic reagents to tumor cells, thus minimizing full-body toxicity. The antibodies may also be used with out added cytotoxin. The antibodies may be detectably labeled or labelable for analytic and diagnostic purposes. The combination of specificity and affinity of the antibodies render them particularly useful.