The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2016

Filed:

May. 11, 2012
Applicants:

Michael Krohn, Lorsch, DE;

Dirk Sombroek, Darmstadt, DE;

Inventors:

Michael Krohn, Lorsch, DE;

Dirk Sombroek, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); C07D 249/08 (2006.01); C07C 255/44 (2006.01); C07C 69/78 (2006.01); C07C 62/30 (2006.01); A23L 1/22 (2006.01); A61K 31/235 (2006.01); A61Q 19/00 (2006.01); A61K 8/36 (2006.01); A61K 8/37 (2006.01); A61K 8/49 (2006.01); A61K 8/69 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A23L 1/22083 (2013.01); A23L 1/22091 (2013.01); A61K 8/36 (2013.01); A61K 8/37 (2013.01); A61K 8/49 (2013.01); A61K 8/496 (2013.01); A61K 8/69 (2013.01); A61K 31/235 (2013.01); A61Q 19/00 (2013.01); C07C 62/30 (2013.01); C07C 69/78 (2013.01); C07C 255/44 (2013.01); C07D 249/08 (2013.01); A61K 2800/782 (2013.01);
Abstract

The present invention relates to the use of compounds which are capable of attenuating skin irritation when they are applied to the skin. Skin irritation can be caused, inter alia, by ingredients of cosmetic or pharmaceutical compositions and/or environmental irritants. In particular, the present invention relates to compounds having the property of antagonizing the activation of the transient receptor potential (TRP) ankyrin 1 (TRPA1) ion channel and the use of said compounds as soothing agents. Such compounds can be used in many fields, particularly in personal-care products, cosmetics, textile and packaging products, pharmaceutical compositions, medical devices, and foodstuffs. The present invention further relates to products and/or pharmaceutical compositions containing said compounds. The present invention also relates to the use of the compounds described herein for the modulation of the taste of a food product.


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