The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
May. 18, 2011
Thomas Rothmann, Langenfeld, DE;
Irina Nazarenko, Gaithersburg, MD (US);
Dominic O'neil, Hilden, DE;
Arvind Virmani, Gaithersburg, MD (US);
Brian Lowe, Olney, MD (US);
Shiuli Agarwal, Somerville, MA (US);
Holly Basham, Reisterstown, MD (US);
Thomas Rothmann, Langenfeld, DE;
Irina Nazarenko, Gaithersburg, MD (US);
Dominic O'Neil, Hilden, DE;
Arvind Virmani, Gaithersburg, MD (US);
Brian Lowe, Olney, MD (US);
Shiuli Agarwal, Somerville, MA (US);
Holly Basham, Reisterstown, MD (US);
QIAGEN GAITHRESBURG, INC, Gaithersburg, MD (US);
Abstract
Methods and materials for determining the presence of at least one nucleic acid in a sample are provided, said methods comprising (1) a purification step using sequence specific hybrid capture; (2) an amplification step; and (3) a detection step comprising contacting the target nucleic acid with a plurality of detectably labeled nucleic acid detection probes, wherein each (a) bears a different detectable label from the other detection probes, and/or (b) has a different melting temperature from probes bearing the same detectable label. Also disclosed are compositions and kits for use in such a method.