The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 16, 2016
Filed:
Oct. 26, 2015
Applicant:
Indena S.p.a., Milan, IT;
Inventors:
Maria Luz Bellido Cabello De Alba, Cordoba, ES;
Giovanni Appendino, Cordoba, ES;
Alberto Pagani, Cordoba, ES;
Eduardo Munoz Blanco, Cordoba, ES;
Assignee:
INDENA S.P.A., Milan, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 45/85 (2006.01); C07C 45/78 (2006.01); C07C 45/80 (2006.01); C07C 67/60 (2006.01); C07C 45/65 (2006.01); B01D 15/08 (2006.01); C07C 67/08 (2006.01); C07D 319/08 (2006.01);
U.S. Cl.
CPC ...
C07C 45/85 (2013.01); B01D 15/08 (2013.01); C07C 45/65 (2013.01); C07C 45/78 (2013.01); C07C 45/80 (2013.01); C07C 67/08 (2013.01); C07C 67/60 (2013.01); C07D 319/08 (2013.01);
Abstract
The present invention relates to a new method for isolating ingenol (CHO) from mixtures of diterpenoid esters and ingenol esters in a single step. Ingenol isolated by means of this method can be used as a precursor for the synthesis of biologically active ingenol derivatives, such as ingenol-3-angelate and ingenol-3-tigliate.