The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 09, 2016

Filed:

May. 14, 2013
Applicant:

Shanghai Righthand Pharmtech. Co., Ltd., Shanghai, CN;

Inventors:

Haiping Wang, Shanghai, CN;

Cheng Chi, Shanghai, CN;

Zhengming Chi, Shanghai, CN;

Jin Wang, Shanghai, CN;

Guanyu Xu, Shanghai, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 303/02 (2006.01); C07C 309/04 (2006.01); C07C 233/18 (2006.01); C07C 309/29 (2006.01); C07C 309/30 (2006.01);
U.S. Cl.
CPC ...
C07C 233/18 (2013.01); C07C 303/02 (2013.01); C07C 309/04 (2013.01); C07C 309/29 (2013.01); C07C 309/30 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to an Agomelatine sulfuric acid complex in formula (I) and the preparation method thereof (HX=HSO, RSOH (R═CH, Ph, 4-CHPh)). The solubility of the Agomelatine sulfuric acid complex obtained by the method of the present invention is significantly improved compared with Agomelatine, has good stability and higher purity, and is suitable for application in finished-product medicinal preparations. The preparation process is quite simple, and a product with high purity can be obtained without special operations.


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