IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9404129 B1

PDFFull Text
Date of Patent:
Aug. 02, 2016

Filed:

Oct. 15, 2014

Metabolically engineered cells for the production of resveratrol or an oligomeric or glycosidically-bound derivative thereof

Applicant:

Evolva SA, Reinach, CH;

Inventors:

Michael Katz, Malmo, SE;

Hans Peter Smits, Holte, DK;

Jochen Forster, Copenhagen, DK;

Jens Bredel Nielsen, Charlottenlund, DK;

Assignee:

Evolva SA, Reinach, CH;

Attorney:

McDonnell Boehnen Hulbert & Berghoff LLP

Primary Examiner:

Iqbal H Chowdhury

Int. Cl.
CPC ...
C12N 1/20 (2006.01); C12N 1/00 (2006.01); C12P 7/22 (2006.01); C07H 21/04 (2006.01); C12P 23/00 (2006.01); C12N 9/10 (2006.01); C12N 9/02 (2006.01); C12N 9/88 (2006.01); C12N 9/00 (2006.01); C12N 15/52 (2006.01); C12P 7/42 (2006.01); A23C 3/08 (2006.01); A61K 31/05 (2006.01);
U.S. Cl.
CPC ...
C12P 7/22 (2013.01); A23C 3/08 (2013.01); A61K 31/05 (2013.01); C12N 9/0042 (2013.01); C12N 9/0073 (2013.01); C12N 9/1029 (2013.01); C12N 9/1037 (2013.01); C12N 9/88 (2013.01); C12N 9/93 (2013.01); C12N 15/52 (2013.01); C12P 7/42 (2013.01); C12P 23/00 (2013.01); C12Y 203/01074 (2013.01); C12Y 106/02004 (2013.01); C12Y 114/13011 (2013.01); C12Y 403/01005 (2013.01); C12Y 602/01012 (2013.01); C12Y 604/01002 (2013.01); Y02P 20/52 (2015.11);
Abstract

A recombinant micro-organism producing resveratrol by a pathway in which phenylalanine ammonia lyase (PAL) produces trans-cinnamic acid from phenylalanine, cinnamate 4-hydroxylase (C4H) produces 4-coumaric acid from said trans-cinnamic acid, 4-coumarate-CoA ligase (4CL) produces 4-coumaroyl CoA from said 4-coumaric acid, and resveratrol synthase (VST) produces said resveratrol from said 4-coumaroyl CoA, or in which L-phenylalanine- or tyrosine-ammonia lyase (PAL/TAL) produces 4-coumaric acid, 4-coumarate-CoA ligase (4CL) produces 4-coumaroyl CoA from said 4-coumaric acid, and resveratrol synthase (VST) produces said resveratrol from said 4-coumaroyl CoA. The micro-organism may be a yeast, fungus or bacterium including, or

Find Patent Forward Citations

Loading…