The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 12, 2016
Filed:
May. 08, 2015
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Christine E. Brotherton-Pleiss, Sunnyvale, CA (US);
Shawn David Erickson, Leonia, NJ (US);
Hongju Li, Edison, NJ (US);
Sung-Sau So, Verona, NJ (US);
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 413/06 (2006.01); C07D 403/06 (2006.01); C07D 401/06 (2006.01); C07D 271/107 (2006.01);
U.S. Cl.
CPC ...
C07D 413/06 (2013.01); C07D 271/107 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 413/14 (2013.01);
Abstract
The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists of the TRPA1 channel and may be useful in treating inflammatory diseases and disorders associated with that channel.