The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 2016
Filed:
Apr. 28, 2011
Thierry Bettinger, Peillonnex, FR;
Feng Yan, Grand-Lancy, CH;
Sophie Mehier-humbert, Cruseilles, FR;
Peter Frinking, Geneva, CH;
Thierry Bettinger, Peillonnex, FR;
Feng Yan, Grand-Lancy, CH;
Sophie Mehier-Humbert, Cruseilles, FR;
Peter Frinking, Geneva, CH;
BRACCO SUISSE S.A., Manno, CH;
Abstract
Composition comprising gas filled microcapsules and a bioactive agent, useful for an ultrasound-mediated delivery of said bioactive agent. The microcapsules comprise a relatively stiff shell of polymeric or lipid material and have in particular a resistance to a mechanical index of at least 0.15, while the bioactive agent is substantially unbound to the shell of the microcapsules. The composition of the invention is particularly suitable for effectively delivering a genetic material into a cell, upon exposure of the composition to a level of acoustic pressure capable of destroying a portion of the microcapsules and releasing the gas contained therein.