The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 17, 2016

Filed:

Mar. 24, 2011
Applicants:

Anastasia Khvorova, Westborough, MA (US);

William Salomon, Worcester, MA (US);

Joanne Kamens, Newton, MA (US);

Dmitry Samarsky, Westborough, MA (US);

Tod M. Woolf, Sudbury, MA (US);

Pamela A. Pavco, Longmont, CO (US);

Lyn Libertine, Framingham, MA (US);

James Cardia, Franklin, MA (US);

Karen G. Bulock, Mendon, MA (US);

Inventors:

Anastasia Khvorova, Westborough, MA (US);

William Salomon, Worcester, MA (US);

Joanne Kamens, Newton, MA (US);

Dmitry Samarsky, Westborough, MA (US);

Tod M. Woolf, Sudbury, MA (US);

Pamela A. Pavco, Longmont, CO (US);

Lyn Libertine, Framingham, MA (US);

James Cardia, Franklin, MA (US);

Karen G. Bulock, Mendon, MA (US);

Assignee:

RXi Pharmaceuticals Corporation, Marlborough, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1136 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/3341 (2013.01); C12N 2310/3515 (2013.01); C12N 2320/32 (2013.01); C12N 2320/52 (2013.01);
Abstract

The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal and fibrotic applications.


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