The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2016
Filed:
Apr. 11, 2012
Sami Jannin, Bremblens, CH;
Antonio Giuseppe Gianotti, Heidelberg, DE;
Joost Lohman, Kenilworth, GB;
Frank Engelke, Rheinstetten, DE;
Roberto Melzi, Pavia, IT;
Aurélien Bornet, Haute-Nendaz, CH;
Geoffrey Bodenhausen, Paris, FR;
Sami Jannin, Bremblens, CH;
Antonio Giuseppe Gianotti, Heidelberg, DE;
Joost Lohman, Kenilworth, GB;
Frank Engelke, Rheinstetten, DE;
Roberto Melzi, Pavia, IT;
Aurélien Bornet, Haute-Nendaz, CH;
Geoffrey Bodenhausen, Paris, FR;
Bruker BioSpin AG, Faellanden, CH;
Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, CH;
Abstract
A method for producing hyperpolarized sample material for use in magnetic resonance investigations involves preparing a target material containing high γ nuclei with a short T, a polarizing agent with a broad EPR line, and low γ nuclei with a long T. The polarizing agent in the target material is irradiated with microwave radiation, wherein the target material is at a cryogenic temperature and exposed to a static magnetic field B≧4.0 T, thus polarizing the high γ nuclei by DNP, and the polarization is transferred from the high γ nuclei to the low γ nuclei by Cross Polarization. A dissolved sample material is prepared containing the hyperpolarized low γ nuclei from the target material. Nuclei with a long longitudinal relaxation time Tcan thereby be quickly hyperpolarized to a high polarization level.