The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2016

Filed:

Oct. 14, 2010
Applicants:

Thomas Flaig, Englewood, CO (US);

Arthur E. Frankel, Temple, TX (US);

Andrew Thorburn, Denver, CO (US);

Michael L. Glode, Golden, CO (US);

Inventors:

Thomas Flaig, Englewood, CO (US);

Arthur E. Frankel, Temple, TX (US);

Andrew Thorburn, Denver, CO (US);

Michael L. Glode, Golden, CO (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 13/10 (2006.01); A61K 38/00 (2006.01); A61K 38/18 (2006.01); C07K 19/00 (2006.01); C07K 14/485 (2006.01); C07K 14/34 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
C07K 14/485 (2013.01); A61K 38/16 (2013.01); A61K 38/164 (2013.01); A61K 38/1808 (2013.01); C07K 14/34 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention provides methods and compositions for treating bladder cancer. In particular, the present invention provides a fusion protein comprising a toxin moiety that is linked to an epithelial growth factor (EGF) moiety. The toxin moiety and the EGF moiety can be linked optionally via a linker. Typically, the fusion protein is administered intravesically into the cancerous bladder.


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