The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2016

Filed:

Nov. 27, 2013
Applicant:

Fluidigm Corporation, South San Francisco, CA (US);

Inventors:

Geoffrey Facer, Lane Cove, AU;

Brian Fowler, San Mateo, CA (US);

Emerson Cheung Quan, South San Francisco, CA (US);

Marc Unger, San Mateo, CA (US);

Assignee:

Fluidigm Corporation, South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G05D 11/02 (2006.01); F16K 99/00 (2006.01); B01F 5/02 (2006.01); B01F 13/00 (2006.01); C12Q 1/68 (2006.01); G01N 21/75 (2006.01); F16K 3/00 (2006.01); G01N 21/03 (2006.01);
U.S. Cl.
CPC ...
F16K 99/0015 (2013.01); B01F 5/02 (2013.01); B01F 13/0059 (2013.01); B01L 3/502707 (2013.01); B01L 3/502738 (2013.01); C12Q 1/686 (2013.01); F16K 99/0026 (2013.01); F16K 99/0059 (2013.01); B01L 2200/10 (2013.01); B01L 2200/12 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0874 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/123 (2013.01); B01L 2400/0481 (2013.01); B01L 2400/0638 (2013.01); F16K 2099/008 (2013.01); F16K 2099/0084 (2013.01); G01N 2021/0346 (2013.01); Y10T 137/0329 (2015.04); Y10T 137/2164 (2015.04); Y10T 137/2169 (2015.04); Y10T 137/2559 (2015.04); Y10T 137/2655 (2015.04); Y10T 137/2688 (2015.04); Y10T 137/87249 (2015.04);
Abstract

Multilevel microfluidic devices include a control line that can simultaneously actuate valves for both sample and reagent lines. Microfluidic devices are configured to contain a first reagent in a first chamber and a second reagent in a second chamber, where either or both of the first and second reagents are contained at a desired or selected pressure. Operation of a microfluidic device includes transmitting second reagent from the second chamber to the first chamber, for mixing or contact with the first reagent. Microfluidic device features such as channels, valves, chambers, can be at least partially contained, embedded, or formed by or within one or more layers or levels of an elastomeric block.


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