The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2016

Filed:

Feb. 18, 2010
Applicants:

John Mcbride, Lyme, NH (US);

Mark Mellon, Grantham, NH (US);

Vineet Rajgarhia, Dublin, CA (US);

Elena E. Brevnova, Lebanon, NH (US);

Erin Wiswall, Danbury, NH (US);

David A. Hogsett, Grantham, NH (US);

Danie Lagrange, Durbanville, ZA;

Shaunita Rose, Strand, ZA;

Emile Van Zyl, Stellenbosch, ZA;

Inventors:

John McBride, Lyme, NH (US);

Mark Mellon, Grantham, NH (US);

Vineet Rajgarhia, Dublin, CA (US);

Elena E. Brevnova, Lebanon, NH (US);

Erin Wiswall, Danbury, NH (US);

David A. Hogsett, Grantham, NH (US);

Danie LaGrange, Durbanville, ZA;

Shaunita Rose, Strand, ZA;

Emile Van Zyl, Stellenbosch, ZA;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/10 (2006.01); C07K 14/33 (2006.01); C12N 15/81 (2006.01); C12N 9/24 (2006.01); C12N 9/42 (2006.01);
U.S. Cl.
CPC ...
C12P 7/10 (2013.01); C07K 14/33 (2013.01); C12N 9/2402 (2013.01); C12N 9/248 (2013.01); C12N 9/2437 (2013.01); C12N 9/2445 (2013.01); C12N 15/81 (2013.01); C12Y 302/01004 (2013.01); C12Y 302/01008 (2013.01); C12Y 302/01021 (2013.01); C12Y 302/01037 (2013.01); C12Y 302/01091 (2013.01); C07K 2319/035 (2013.01); C07K 2319/70 (2013.01); Y02E 50/16 (2013.01); Y02P 20/52 (2015.11);
Abstract

The present invention relates to the engineering and expression of heterologous cellulosomes in microorganisms in order to facilitate the conversion of biomass to useful products. In some embodiments, the invention relates to the expression of scaffoldin proteins which form the nucleus of a cellulosome. Cellulases or other biomass-degrading enzymes can be non-covalently linked to the scaffoldin protein by virtue of a dockerin domain-cohesin domain interaction.


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